Anthony Volmink comes into the Lions team at left wing and Marnitz Boshoff is back at flyhalf for the Lions as they prepare to face the Highlanders in a Super Rugby clash in Dunedin on Saturday.
Volmink is replacing Courtnall Skosan and Boshoff is in at the expense of Elton Jantjies who started in last week's 38-8 loss to the Chiefs in Hamilton.
Up front, coach Johan Ackermann has made just one change, with MB Lusaseni starting at lock in place of Franco Mostert.
On the bench, Corné Fourie has been called up to provide prop cover, while Rudi Mathee and Warwick Teckenburg are also new inclusions.
The Lions team is:
15. Chrysander Botha, 14. Courtnall Skosan, 13. Lionel Mapoe, 12. Stefan Watermeyer, 11. Anthony Volmink, 10. Marnitz Boshoff, 9. Faf de Klerk, 8. Warren Whiteley (c), 7. Derick Minnie, 6. Jaco Kriel, 5. Martin Muller, 4. MB Lusaseni, 3. Julian Redelinghuys, 2. Robbie Coetzee, 1. Schalk van der Merwe. Replacements: 16. Armand van der Merwe, 17. Corne Fourie, 18. Jacques van Rooyen, 19. Rudi Mathee, 20. Warwick Teckenburg, 21. Ross Cronje, 22. Elton Jantjies, 23. JW Jonker